KLHDC10

Across TCGA pan-cancer cohorts, KLHDC10 mass-spec protein differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of KLHDC10’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where KLHDC10 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types KLHDC10 is over-expressed in tumor.

LUAD, CCRCC, and LSCC are the cancer types where KLHDC10 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KLHDC10 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	II,III,IV	+0.641	<.001	8	view →
CCRCC	All	II,III,IV	+0.259	.004	6	view →
LSCC	All	All	+0.171	.001	6	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

KLHDC10–LUAD

Open the LUAD breakdown →