KLF7P1

Across TCGA pan-cancer cohorts, KLF7P1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of KLF7P1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where KLF7P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types KLF7P1 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

HNSC and BLCA are the cancer types where KLF7P1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KLF7P1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.054	<.001	10	view →
BLCA	Male	IV	−0.165	.027	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

KLF7P1–HNSC

Open the HNSC breakdown →