KLF4P1

Across TCGA patient cohorts, KLF4P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,664 significant associations in total. STAD shows the largest number of these associations.

The most reproducible KLF4P1-associated GO terms across cancer lineages are Regulation of Ras protein signal transduction, Negative regulation of mRNA metabolic process, and Establishment of protein localization to vacuole. Each is linked with KLF4P1 in more than 16 cancer types. Because this analysis shows association rather than direction, both KLF4P1-to-partner and partner-to-KLF4P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of Ras protein signal transduction grouped by KLF4P1-low versus KLF4P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF4P1→partner) and Y-score (partner→KLF4P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of Ras protein signal transduction →	+0.056	+0.268	<.001	<.001	3	17
STAD	Negative regulation of mRNA metabolic process →	+0.063	+0.254	<.001	<.001	3	16
STAD	Establishment of protein localization to vacuole →	+0.063	+0.253	<.001	<.001	3	16
STAD	Transport along microtubule →	+0.053	+0.265	<.001	<.001	3	16
STAD	RNA methylation →	+0.053	+0.257	<.001	<.001	3	16
ESCA	Cytoskeleton-dependent intracellular transport →	+0.064	+0.314	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,664 associations by consensus.

Regulation of Ras protein signal transduction by KLF4P1 expression — STAD

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