KLF2

Across TCGA patient cohorts, KLF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 22,426 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLF2-associated proteins across cancer lineages are CAVIN2, OGN, and OLFML1. Each is linked with KLF2 in more than 9 cancer types. Because this analysis shows association rather than direction, both KLF2-to-partner and partner-to-KLF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF2 versus CAVIN2 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF2→partner) and Y-score (partner→KLF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CAVIN2 →	+0.805	+1.200	<.001	<.001	3	10
COAD	OGN →	+1.224	+1.169	<.001	<.001	3	9
UCEC	OLFML1 →	+1.058	+0.923	<.001	<.001	3	9
BRCA	SOD3 →	+0.806	+0.910	<.001	.002	3	9
OV	LUM →	+0.921	+0.930	<.001	<.001	3	9
UCEC	CAVIN2_S203 →	+0.822	+0.961	.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,426 associations by consensus.

KLF2 vs CAVIN2 — BRCA

Explore this scatter interactively →