KLF18

Across TCGA patient cohorts, KLF18 RNA expression is significantly associated with the protein abundance of many other proteins, with 1,656 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLF18-associated proteins across cancer lineages are PLEC_T2735, PLEC_T2886, and EPB41L1_S544. Each is linked with KLF18 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF18-to-partner and partner-to-KLF18 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLF18 versus PLEC_T2735 in BRCA, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF18→partner) and Y-score (partner→KLF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PLEC_T2735 →	+0.779	+0.010	<.001	.005	3	2
BRCA	PLEC_T2886 →	+0.779	+0.010	<.001	.005	3	2
PDAC	EPB41L1_S544 →	-0.591	-0.034	.003	.009	3	2
BRCA	SCARF1 →	+0.555	+0.015	<.001	.001	3	2
GBM	ERF_S185 →	+0.591	+0.074	<.001	<.001	3	2
GBM	IFFO2 →	+0.438	+0.099	.007	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,656 associations by consensus.

KLF18 vs PLEC_T2735 — BRCA

Explore this scatter interactively →