KLF18

Across TCGA cell cohorts, KLF18 RNA expression is significantly associated with the go_rna of many other GO terms, with 279 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KLF18-associated GO terms across cancer lineages are Schwann cell differentiation, Regulation of protein localization to cell-cell junction, and Protein localization to membrane. Each is linked with KLF18 in more than 2 cancer types. Because this analysis shows association rather than direction, both KLF18-to-partner and partner-to-KLF18 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Schwann cell differentiation grouped by KLF18-low versus KLF18-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF18→partner) and Y-score (partner→KLF18) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Schwann cell differentiation →	+0.083	+0.004	<.001	.006	3	3
BLOOD_Lymphoma	Regulation of protein localization to cell-cell junction →	+0.102	+0.004	.006	.005	3	3
BLOOD_Lymphoma	Protein localization to membrane →	+0.034	+0.004	<.001	.006	3	3
PANCREAS	Regulation of blood vessel endothelial cell migration →	+0.061	+0.004	.002	.007	3	3
SOFT_TISSUE	Granzyme-mediated apoptotic signaling pathway →	+0.111	+0.046	<.001	.009	3	3
BONE	Regulation of protein localization to nucleus →	+0.060	+0.016	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 279 associations by consensus.

Schwann cell differentiation by KLF18 expression — BLOOD_Lymphoma

Explore this box plot interactively →