KLF17P1

Across TCGA pan-cancer cohorts, KLF17P1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated KLF17P1 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher KLF17P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KLF17P1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and TGCT show a favorable association.

THCA, SARC, and LIHC are the cancer types where KLF17P1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Median	III,IV	0.540	0.808	<.001	91	view →
SARC	DFS	Tertile	All	0.104	0.425	<.001	36	view →
LIHC	DFS	Tertile	III,IV	0.071	0.439	<.001	36	view →
UVM	OS	Tertile	All	0.303	0.821	<.001	30	view →
PAAD	OS	Quartile	II,III,IV	0.748	0.353	.022	19	view →
READ	DFS	Tertile	IV	0.306	0.671	.012	18	view →
KIRC	DFS	Tertile	All	0.727	0.864	.012	14	view →
KIRP	OS	Tertile	All	0.486	0.785	.007	10	view →
COAD	OS	Tertile	IV	0.082	0.658	.008	9	view →
OV	OS	Tertile	IV	0.295	0.545	.017	8	view →
TGCT	DFS	Tertile	All	0.965	0.793	.030	6	view →
LUAD	OS	Tertile	II,III,IV	0.665	0.781	.045	2	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

KLF17P1–THCA (DFS)

Open the THCA breakdown →