KLF13

Across TCGA pan-cancer cohorts, KLF13 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated KLF13 data layer compared with 26 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher KLF13 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated KLF13 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

PDAC, CCRCC, and UCEC are the cancer types where KLF13 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Median	III,IV	0.308	0.863	.006	23	view →
CCRCC	DFS	Quartile	II,III,IV	0.140	0.830	.038	6	view →
UCEC	DFS	Median	All	1.000	0.938	.026	4	view →
HNSC	DFS	Quartile	III,IV	0.808	0.912	.026	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

KLF13–PDAC (DFS)

Open the PDAC breakdown →