KLF13

Across TCGA cell cohorts, KLF13 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,039 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KLF13-associated GO terms across cancer lineages are Negative regulation of erythrocyte differentiation, Regulation of protein localization to cell periphery, and Acute inflammatory response to antigenic stimulus. Each is linked with KLF13 in more than 12 cancer types. Because this analysis shows association rather than direction, both KLF13-to-partner and partner-to-KLF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of erythrocyte differentiation grouped by KLF13-low versus KLF13-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF13→partner) and Y-score (partner→KLF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of erythrocyte differentiation →	+0.206	+1.467	<.001	<.001	3	13
BONE	Regulation of protein localization to cell periphery →	+0.095	+0.806	<.001	.003	3	9
OESOPHAGUS	Acute inflammatory response to antigenic stimulus →	-2.004	-1.600	<.001	.003	3	9
BREAST	Hypersensitivity →	-1.057	-1.493	<.001	<.001	3	9
LUNG_NSCLC_LUSC	Peptidyl-serine phosphorylation →	+0.080	+1.608	.001	.005	3	8
LUNG_SCLC	Regulation of erythrocyte differentiation →	+0.093	+1.119	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,039 associations by consensus.

Negative regulation of erythrocyte differentiation by KLF13 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →