KLF13

Across TCGA cell cohorts, KLF13 mutation is significantly associated with the RNA expression of many other genes, with 23 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KLF13-associated genes across cancer lineages are APCS, KRTAP10-1, and SERPINA7. Each is linked with KLF13 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF13-to-partner and partner-to-KLF13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, APCS grouped by KLF13-low versus KLF13-high in KIDNEY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF13→partner) and Y-score (partner→KLF13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	APCS →	+0.033	+5.000	<.001	.005	3	1
KIDNEY	KRTAP10-1 →	+0.020	+5.000	<.001	.005	3	1
BLOOD_Myeloma	SERPINA7 →	+0.459	+4.807	<.001	.006	3	1
BLOOD_Myeloma	C1orf158 →	+0.053	+4.807	<.001	.006	3	1
LUNG_NSCLC_LUAD	OR4A47 →	+0.018	+5.228	<.001	.005	3	1
BLOOD_Leukemia	NME5 →	+0.259	+3.379	.003	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

APCS by KLF13 expression — KIDNEY

Explore this box plot interactively →