KLF10

Across TCGA cell cohorts, KLF10 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,711 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KLF10-associated GO terms across cancer lineages are Proteinogenic amino acid metabolic process, Proteinogenic amino acid catabolic process, and Alpha-amino acid metabolic process. Each is linked with KLF10 in more than 13 cancer types. Because this analysis shows association rather than direction, both KLF10-to-partner and partner-to-KLF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Proteinogenic amino acid metabolic process grouped by KLF10-low versus KLF10-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF10→partner) and Y-score (partner→KLF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Proteinogenic amino acid metabolic process →	-0.070	-0.888	<.001	<.001	3	14
BREAST	Proteinogenic amino acid catabolic process →	-0.102	-1.187	<.001	<.001	3	14
BONE	Alpha-amino acid metabolic process →	-0.082	-0.787	<.001	<.001	3	14
BREAST	Amino acid catabolic process →	-0.081	-0.766	<.001	<.001	3	13
URINARY_TRACT	Cellular response to environmental stimulus →	+0.048	+1.223	<.001	<.001	3	12
URINARY_TRACT	Cellular response to abiotic stimulus →	+0.048	+1.223	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,711 associations by consensus.

Proteinogenic amino acid metabolic process by KLF10 expression — BONE

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