KLF10

Across TCGA cell cohorts, KLF10 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KLF10-associated genes across cancer lineages are MS4A10, IL26, and SFTPA1. Each is linked with KLF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both KLF10-to-partner and partner-to-KLF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MS4A10 grouped by KLF10-low versus KLF10-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLF10→partner) and Y-score (partner→KLF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	MS4A10 →	+0.006	+4.867	<.001	.009	3	1
LARGE_INTESTINE	IL26 →	+0.423	+3.115	<.001	.004	3	1
LARGE_INTESTINE	SFTPA1 →	+0.090	+3.519	.004	.007	3	1
LARGE_INTESTINE	CD93 →	+0.056	+2.994	<.001	.006	3	1
LARGE_INTESTINE	HMX3 →	+0.829	+3.794	<.001	.001	3	1
LARGE_INTESTINE	KIR3DL2 →	+0.064	+2.878	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

MS4A10 by KLF10 expression — BLOOD_Lymphoma

Explore this box plot interactively →