KLC3

Across TCGA patient cohorts, KLC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,712 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KLC3-associated proteins across cancer lineages are KLC3_S466, KLC3_S173, and GMDS. Each is linked with KLC3 in more than 7 cancer types. Because this analysis shows association rather than direction, both KLC3-to-partner and partner-to-KLC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLC3 versus KLC3_S466 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KLC3→partner) and Y-score (partner→KLC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	KLC3_S466 →	+1.120	+0.759	<.001	<.001	3	8
PDAC	KLC3_S173 →	+0.905	+0.952	<.001	<.001	3	6
PDAC	GMDS →	-0.590	-0.558	<.001	<.001	3	5
LSCC	KLC3_S502 →	+0.988	+1.010	<.001	<.001	3	5
LUAD	SGSM3 →	-0.546	-0.811	<.001	<.001	3	5
UCEC	DCTN1 →	-0.152	-0.636	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,712 associations by consensus.

KLC3 vs KLC3_S466 — OV

Explore this scatter interactively →