KLC2

Across TCGA patient cohorts, KLC2 protein abundance is significantly associated with the RNA expression of many other genes, with 9,020 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KLC2-associated genes across cancer lineages are ABI3BP, KIF5B, and KIFBP. Each is linked with KLC2 in more than 5 cancer types. Because this analysis shows association rather than direction, both KLC2-to-partner and partner-to-KLC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KLC2 versus ABI3BP in UCEC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KLC2→partner) and Y-score (partner→KLC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABI3BP →	-1.027	-0.205	.002	.002	3	6
UCEC	KIF5B →	+0.628	+0.242	.001	.003	3	6
UCEC	KIFBP →	+0.571	+0.272	.002	<.001	3	5
LSCC	NUDT5 →	+0.676	+0.376	<.001	<.001	3	4
OV	LINC01133 →	-1.756	-0.344	<.001	<.001	3	4
UCEC	LINC01354 →	-0.711	-0.253	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,020 associations by consensus.

KLC2 vs ABI3BP — UCEC

Explore this scatter interactively →