KL

Across TCGA patient cohorts, KL RNA expression is significantly associated with the protein abundance of many other proteins, with 15,200 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KL-associated proteins across cancer lineages are FERMT2, KANK2, and NID1. Each is linked with KL in more than 8 cancer types. Because this analysis shows association rather than direction, both KL-to-partner and partner-to-KL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KL versus FERMT2 in BRCA, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KL→partner) and Y-score (partner→KL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	FERMT2 →	+0.843	+0.664	<.001	<.001	3	9
BRCA	KANK2 →	+0.889	+0.816	<.001	<.001	3	8
UCEC	NID1 →	+0.711	+0.706	<.001	<.001	3	8
UCEC	PARVA →	+0.558	+0.479	<.001	.001	3	8
COAD	RPS3A →	-0.241	-0.377	<.001	<.001	3	7
BRCA	HSPA12B →	+0.545	+0.525	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,200 associations by consensus.

KL vs FERMT2 — BRCA

Explore this scatter interactively →