KL

Across TCGA patient cohorts, KL protein abundance is significantly associated with the RNA expression of many other genes, with 3,301 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible KL-associated genes across cancer lineages are CXCR1, CEACAM3, and NSUN3. Each is linked with KL in more than 2 cancer types. Because this analysis shows association rather than direction, both KL-to-partner and partner-to-KL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KL versus CXCR1 in GBM, with a Pearson correlation of 0.66.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KL→partner) and Y-score (partner→KL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CXCR1 →	+1.922	+2.535	<.001	<.001	3	3
UCEC	CEACAM3 →	+0.821	+2.086	.002	<.001	3	3
GBM	NSUN3 →	-0.508	-2.140	.003	.003	3	3
GBM	MEFV →	+0.936	+1.653	.003	.004	3	2
GBM	AQP9 →	+1.730	+1.832	.004	.002	3	2
PDAC	FFAR2 →	+0.937	+1.010	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,301 associations by consensus.

KL vs CXCR1 — GBM

Explore this scatter interactively →