KL

Across TCGA cell cohorts, KL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,284 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KL-associated GO terms across cancer lineages are Vacuolar transport, Lysosomal transport, and Golgi vesicle transport. Each is linked with KL in more than 7 cancer types. Because this analysis shows association rather than direction, both KL-to-partner and partner-to-KL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vacuolar transport grouped by KL-low versus KL-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KL→partner) and Y-score (partner→KL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Vacuolar transport →	+0.053	+0.259	<.001	.009	3	8
LUNG_NSCLC_LUSC	Lysosomal transport →	+0.067	+0.170	<.001	.003	2	8
LIVER	Golgi vesicle transport →	+0.055	+0.108	.001	.002	3	6
OVARY	Vesicle budding from membrane →	+0.059	+0.085	<.001	.002	2	7
LUNG_NSCLC_LUAD	Regulation of myoblast fusion →	+0.046	+0.187	.001	.009	2	7
LUNG_NSCLC_LUSC	Endosome to lysosome transport →	+0.075	+0.122	<.001	<.001	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,284 associations by consensus.

Vacuolar transport by KL expression — OVARY

Explore this box plot interactively →