KIZ

Across TCGA cell cohorts, KIZ RNA expression is significantly associated with the go_rna of many other GO terms, with 2,399 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIZ-associated GO terms across cancer lineages are Thymidine biosynthetic process, 2'-deoxyribonucleoside biosynthetic process, and Pyrimidine deoxyribonucleoside biosynthetic process. Each is linked with KIZ in more than 9 cancer types. Because this analysis shows association rather than direction, both KIZ-to-partner and partner-to-KIZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Thymidine biosynthetic process grouped by KIZ-low versus KIZ-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIZ→partner) and Y-score (partner→KIZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Thymidine biosynthetic process →	-0.179	-1.548	.008	.003	3	10
OESOPHAGUS	2'-deoxyribonucleoside biosynthetic process →	-0.179	-1.548	.008	.003	3	10
OESOPHAGUS	Pyrimidine deoxyribonucleoside biosynthetic process →	-0.179	-1.548	.008	.003	3	10
SOFT_TISSUE	Positive regulation by virus of viral protein levels in host cell →	+0.109	+0.831	<.001	.001	3	9
BLOOD_Myeloma	Nuclear mRNA surveillance →	+0.055	+0.864	.008	.001	3	8
PANCREAS	Regulation of organelle assembly →	+0.036	+0.758	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,399 associations by consensus.

Thymidine biosynthetic process by KIZ expression — OESOPHAGUS

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