KIZ-AS1

Across TCGA pan-cancer cohorts, KIZ-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated KIZ-AS1 data layer.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KIZ-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIZ-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

KIRP, KIRC, and ACC are the cancer types where KIZ-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	All	0.352	0.704	<.001	128	view →
KIRC	DFS	Tertile	All	0.445	0.716	<.001	92	view →
ACC	OS	Tertile	All	0.637	0.961	.001	84	view →
UCS	DFS	Quartile	III,IV	0.650	0.074	<.001	56	view →
UCEC	DFS	Tertile	III,IV	0.774	0.504	.007	54	view →
THCA	OS	Tertile	All	0.981	0.997	.002	35	view →
LAML	DFS	Quartile	All	0.530	0.343	.012	32	view →
CESC	DFS	Median	III,IV	0.185	0.717	.002	30	view →
SKCM	DFS	Median	IV	0.055	0.572	.002	18	view →
READ	OS	Median	II,III,IV	1.000	0.847	.008	17	view →
BLCA	DFS	Tertile	All	0.585	0.453	.011	15	view →
PRAD	DFS	Tertile	All	0.835	0.922	.008	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

KIZ-AS1–KIRP (DFS)

Open the KIRP breakdown →