KITLG

Across TCGA patient cohorts, KITLG RNA expression is significantly associated with the protein abundance of many other proteins, with 12,296 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible KITLG-associated proteins across cancer lineages are TIMMDC1, NFS1, and LYRM4. Each is linked with KITLG in more than 4 cancer types. Because this analysis shows association rather than direction, both KITLG-to-partner and partner-to-KITLG results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KITLG versus TIMMDC1 in PDAC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KITLG→partner) and Y-score (partner→KITLG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TIMMDC1 →	-0.356	-0.515	.002	<.001	3	5
OV	NFS1 →	-0.407	-0.849	.008	.007	3	5
OV	LYRM4 →	-0.458	-0.839	<.001	<.001	3	5
OV	CCDC58 →	-0.514	-0.961	<.001	<.001	3	4
OV	DIAPH2 →	+0.463	+1.014	<.001	<.001	3	4
LUAD	RPS18 →	-0.332	-0.774	.002	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,296 associations by consensus.

KITLG vs TIMMDC1 — PDAC

Explore this scatter interactively →