KIRREL3

Across TCGA patient cohorts, KIRREL3 protein abundance is significantly associated with the RNA expression of many other genes, with 2,350 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIRREL3-associated genes across cancer lineages are PRODH, SEZ6L, and SOX10. Each is linked with KIRREL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIRREL3-to-partner and partner-to-KIRREL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIRREL3 versus PRODH in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIRREL3→partner) and Y-score (partner→KIRREL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRODH →	+1.015	+0.625	.002	<.001	3	1
GBM	SEZ6L →	+1.721	+0.405	.005	.006	3	1
GBM	SOX10 →	+1.725	+0.446	<.001	<.001	3	1
GBM	SLC16A8 →	+0.852	+0.638	<.001	<.001	3	1
GBM	SEPTIN3 →	+1.266	+0.478	<.001	.001	3	1
GBM	SUN2 →	+0.405	+0.340	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,350 associations by consensus.

KIRREL3 vs PRODH — GBM

Explore this scatter interactively →