KIRREL3

Across TCGA cell cohorts, KIRREL3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,078 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible KIRREL3-associated GO terms across cancer lineages are Positive regulation of coagulation, Actin filament organization, and Positive regulation of hemostasis. Each is linked with KIRREL3 in more than 9 cancer types. Because this analysis shows association rather than direction, both KIRREL3-to-partner and partner-to-KIRREL3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of coagulation grouped by KIRREL3-low versus KIRREL3-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIRREL3→partner) and Y-score (partner→KIRREL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of coagulation →	+0.149	+1.239	.002	<.001	3	10
BREAST	Actin filament organization →	+0.063	+1.066	.003	.002	3	10
SOFT_TISSUE	Positive regulation of hemostasis →	+0.169	+1.255	.001	<.001	3	10
SOFT_TISSUE	Regulation of proteolysis →	+0.088	+1.168	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of blood coagulation →	+0.169	+1.255	.001	<.001	3	10
LIVER	Positive regulation of stress fiber assembly →	+0.146	+2.164	<.001	.009	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,078 associations by consensus.

Positive regulation of coagulation by KIRREL3 expression — SOFT_TISSUE

Explore this box plot interactively →