KIRREL2

Across TCGA patient cohorts, KIRREL2 protein abundance is significantly associated with the RNA expression of many other genes, with 608 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible KIRREL2-associated genes across cancer lineages are PPIL2, PRODH, and PATZ1. Each is linked with KIRREL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIRREL2-to-partner and partner-to-KIRREL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIRREL2 versus PPIL2 in CCRCC, with a Pearson correlation of -0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIRREL2→partner) and Y-score (partner→KIRREL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	PPIL2 →	-0.513	-0.508	<.001	.001	3	1
CCRCC	PRODH →	-1.236	-0.462	.004	<.001	3	1
CCRCC	PATZ1 →	-0.716	-0.564	<.001	.001	3	1
CCRCC	PICK1 →	-0.514	-0.608	.001	<.001	3	1
CCRCC	FBXO7 →	-0.460	-0.514	.001	.001	3	1
CCRCC	MIOX →	-1.784	-0.359	.007	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 608 associations by consensus.

KIRREL2 vs PPIL2 — CCRCC

Explore this scatter interactively →