Across TCGA cell cohorts, KIRREL1 mutation is significantly associated with the RNA expression of many other genes, with 753 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIRREL1-associated genes across cancer lineages are TRMT10A, FFAR3, and LYZL2. Each is linked with KIRREL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIRREL1-to-partner and partner-to-KIRREL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIRREL1→partner) and Y-score (partner→KIRREL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TRMT10A →	+0.701	+3.459	<.001	.001	3	2
LUNG_NSCLC_LUAD	FFAR3 →	+0.014	+3.343	<.001	.005	3	2
LIVER	LYZL2 →	+0.080	+3.977	<.001	.006	3	1
BLOOD_Myeloma	OR10AG1 →	+0.023	+4.807	<.001	.006	3	1
LARGE_INTESTINE	GGA1 →	+0.558	+3.169	.005	.009	3	1
LARGE_INTESTINE	ANKRD54 →	+0.511	+3.389	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 753 associations by consensus.

Exploration

KIRREL1 survival (RNA) · tumor vs normal (RNA) · all KIRREL1 data types