KIR3DX1

Across TCGA patient cohorts, KIR3DX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,757 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIR3DX1-associated proteins across cancer lineages are ICAM3, PIP4K2A, and PTPRC. Each is linked with KIR3DX1 in more than 4 cancer types. Because this analysis shows association rather than direction, both KIR3DX1-to-partner and partner-to-KIR3DX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIR3DX1 versus ICAM3 in BRCA, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR3DX1→partner) and Y-score (partner→KIR3DX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ICAM3 →	+0.611	+0.103	<.001	.003	3	5
GBM	PIP4K2A →	+0.500	+0.127	.001	<.001	3	4
BRCA	PTPRC →	+0.545	+0.077	<.001	<.001	3	4
BRCA	RAC2 →	+0.691	+0.088	<.001	<.001	3	4
OV	ARHGAP25 →	+0.869	+0.051	<.001	.003	3	4
BRCA	ARHGAP25_S512 →	+0.609	+0.117	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,757 associations by consensus.

KIR3DX1 vs ICAM3 — BRCA

Explore this scatter interactively →