KIR3DL2

Across TCGA pan-cancer cohorts, KIR3DL2 mass-spec protein differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of KIR3DL2’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where KIR3DL2 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types KIR3DL2 is over-expressed in tumor.

CCRCC are the cancer types where KIR3DL2 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIR3DL2 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	Male	All	+0.439	.003	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

KIR3DL2–CCRCC

Open the CCRCC breakdown →