KIR3DL1

Across TCGA patient cohorts, KIR3DL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,301 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIR3DL1-associated proteins across cancer lineages are STAT1_S532, TYMP, and XAF1. Each is linked with KIR3DL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIR3DL1-to-partner and partner-to-KIR3DL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIR3DL1 versus STAT1_S532 in BRCA, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR3DL1→partner) and Y-score (partner→KIR3DL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STAT1_S532 →	+0.939	+0.278	<.001	<.001	3	6
COAD	TYMP →	+0.576	+0.424	<.001	<.001	3	5
COAD	XAF1 →	+0.652	+0.425	.001	<.001	3	5
BRCA	TAP1 →	+0.627	+0.284	<.001	<.001	3	4
BRCA	TAPBP →	+0.632	+0.337	<.001	<.001	3	4
LSCC	CLIC2 →	+0.405	+0.128	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,301 associations by consensus.

KIR3DL1 vs STAT1_S532 — BRCA

Explore this scatter interactively →