KIR3DL1

Across TCGA cell cohorts, KIR3DL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 65 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KIR3DL1-associated GO terms across cancer lineages are Uridine metabolic process, Pyrimidine ribonucleoside metabolic process, and Hemoglobin metabolic process. Each is linked with KIR3DL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIR3DL1-to-partner and partner-to-KIR3DL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Uridine metabolic process grouped by KIR3DL1-low versus KIR3DL1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR3DL1→partner) and Y-score (partner→KIR3DL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Uridine metabolic process →	+0.940	+0.009	<.001	.008	3	2
BLOOD_Leukemia	Pyrimidine ribonucleoside metabolic process →	+0.940	+0.009	<.001	.008	3	2
BLOOD_Leukemia	Hemoglobin metabolic process →	+0.177	+0.009	.002	.008	3	1
LIVER	Regulation of mitochondrial DNA metabolic process →	+0.160	+0.011	<.001	.009	3	1
BLOOD_Lymphoma	tRNA surveillance →	-0.058	-0.728	.002	.009	3	1
BLOOD_Lymphoma	Neurotransmitter uptake →	-0.122	-0.732	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 65 associations by consensus.

Uridine metabolic process by KIR3DL1 expression — BLOOD_Leukemia

Explore this box plot interactively →