Across TCGA cell cohorts, KIR2DL4 RNA expression is significantly associated with the go_rna of many other GO terms, with 835 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible KIR2DL4-associated GO terms across cancer lineages are Neutrophil-mediated killing of fungus, Cellular response to ionizing radiation, and Signal transduction in response to DNA damage. Each is linked with KIR2DL4 in more than 6 cancer types. Because this analysis shows association rather than direction, both KIR2DL4-to-partner and partner-to-KIR2DL4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR2DL4→partner) and Y-score (partner→KIR2DL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Neutrophil-mediated killing of fungus →	+0.133	+0.073	.001	.003	3	7
OESOPHAGUS	Cellular response to ionizing radiation →	+0.071	+0.073	.004	.003	3	4
OESOPHAGUS	Signal transduction in response to DNA damage →	+0.071	+0.106	<.001	.001	3	4
BLOOD_Leukemia	Neutrophil extracellular trap formation →	+0.677	+0.239	.001	.008	3	4
CNS	Acetylcholine transport →	+0.748	+0.031	.001	.005	3	3
CNS	Acetate ester transport →	+0.748	+0.031	.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 835 associations by consensus.

Exploration

KIR2DL4 survival (RNA) · tumor vs normal (RNA) · all KIR2DL4 data types