KIR2DL1

Across TCGA cell cohorts, KIR2DL1 RNA expression is significantly associated with the go_rna of many other GO terms, with 139 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIR2DL1-associated GO terms across cancer lineages are Regulation of behavior, Regulation of the force of skeletal muscle contraction, and Regulation of skeletal muscle contraction by chemo-mechanical energy conversion. Each is linked with KIR2DL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both KIR2DL1-to-partner and partner-to-KIR2DL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of behavior grouped by KIR2DL1-low versus KIR2DL1-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIR2DL1→partner) and Y-score (partner→KIR2DL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Regulation of behavior →	-0.058	-0.019	.004	.003	3	3
BLOOD_Leukemia	Regulation of the force of skeletal muscle contraction →	-0.111	-0.017	.001	.007	3	2
BLOOD_Leukemia	Regulation of skeletal muscle contraction by chemo-mechanical energy conversion →	-0.111	-0.017	.001	.007	3	2
BLOOD_Leukemia	Negative regulation of response to endoplasmic reticulum stress →	+0.042	+0.020	.008	.001	3	2
BLOOD_Leukemia	Immune response to tumor cell →	+0.146	+0.017	<.001	.009	3	2
BLOOD_Leukemia	'de novo' NAD+ biosynthetic process from L-tryptophan →	-0.159	-0.018	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

Regulation of behavior by KIR2DL1 expression — BLOOD_Leukemia

Explore this box plot interactively →