KIN

Across TCGA pan-cancer cohorts, KIN Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated KIN data layer compared with 26 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KIN Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated KIN expression acts as an unfavorable survival marker.

KIRC, LUSC, and LIHC are the cancer types where KIN Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.054	0.881	<.001	48	view →
LUSC	OS	Median	All	0.112	0.762	<.001	36	view →
LIHC	OS	Median	All	0.011	0.784	<.001	24	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

KIN–KIRC (OS)

Open the KIRC breakdown →