KIFC3

Across TCGA cell cohorts, KIFC3 mutation is significantly associated with the RNA expression of many other genes, with 374 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIFC3-associated genes across cancer lineages are OPRPN, LRIT2, and OR12D2. Each is linked with KIFC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIFC3-to-partner and partner-to-KIFC3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by KIFC3-low versus KIFC3-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIFC3→partner) and Y-score (partner→KIFC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OPRPN →	+0.060	+5.087	<.001	.004	3	1
URINARY_TRACT	LRIT2 →	+0.036	+5.087	<.001	.004	3	1
URINARY_TRACT	OR12D2 →	+0.136	+5.087	<.001	.004	3	1
LUNG_SCLC	OR4A16 →	+0.023	+4.817	<.001	.001	3	1
OVARY	CLVS2 →	+0.040	+3.113	.009	.004	3	1
OVARY	PRG3 →	+0.019	+3.339	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 374 associations by consensus.

OPRPN by KIFC3 expression — URINARY_TRACT

Explore this box plot interactively →