KIFC2

Across TCGA cell cohorts, KIFC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,355 significant associations in total. BONE shows the largest number of these associations.

The most reproducible KIFC2-associated GO terms across cancer lineages are Cilium-dependent cell motility, Cilium or flagellum-dependent cell motility, and Positive regulation of intracellular steroid hormone receptor signaling pathway. Each is linked with KIFC2 in more than 15 cancer types. Because this analysis shows association rather than direction, both KIFC2-to-partner and partner-to-KIFC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cilium-dependent cell motility grouped by KIFC2-low versus KIFC2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIFC2→partner) and Y-score (partner→KIFC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.104	-1.225	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.104	-1.225	<.001	<.001	3	16
LUNG_SCLC	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.180	+1.376	<.001	.001	3	15
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.180	+1.806	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.249	+1.743	<.001	<.001	3	14
OESOPHAGUS	Flagellated sperm motility →	-0.143	-1.601	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,355 associations by consensus.

Cilium-dependent cell motility by KIFC2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →