KIFC1

Across TCGA pan-cancer cohorts, KIFC1 Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIFC1 data layer compared with 32 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where higher KIFC1 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIFC1 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

KIRP, OV, and BLCA are the cancer types where KIFC1 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRP	DFS	Median	II,III,IV	0.037	0.783	<.001	24	view →
OV	DFS	Median	III,IV	1.000	0.367	.034	6	view →
BLCA	DFS	Median	IV	0.077	0.476	<.001	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	3	view →
SKCM	DFS	Median	III,IV	0.224	0.652	.029	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIFC1–KIRP (DFS)

Open the KIRP breakdown →