KIFC1

Across TCGA pan-cancer cohorts, KIFC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated KIFC1 data layer compared with 32 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher KIFC1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated KIFC1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where KIFC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.734	1.000	.009	19	view →
LSCC	OS	Median	All	0.901	0.738	.005	17	view →
PDAC	DFS	Tertile	III,IV	1.000	0.426	.017	15	view →
LUAD	DFS	Median	All	0.504	0.890	.017	6	view →
HNSC	OS	Quartile	All	0.342	1.000	.034	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

KIFC1–CCRCC (OS)

Open the CCRCC breakdown →