Across TCGA patient cohorts, KIFBP mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIFBP-associated genes across cancer lineages are FOXO3a, INPP4B, and JNK2. Each is linked with KIFBP in more than 1 cancer types. Because this analysis shows association rather than direction, both KIFBP-to-partner and partner-to-KIFBP results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIFBP→partner) and Y-score (partner→KIFBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a →	+0.094	+1.887	.047	.031	3	1
UCEC	INPP4B →	-0.401	-2.459	.007	.019	3	1
UCEC	JNK2 →	+0.332	+2.584	<.001	.011	3	1
UCEC	MSH2 →	-0.296	-3.312	.005	.010	3	1
UCEC	Myosin-IIa_pS1943 →	+0.245	+3.000	.010	.036	3	1
UCEC	Myosin-IIa →	+0.279	+3.707	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

Exploration

KIFBP survival (RNA) · tumor vs normal (RNA) · all KIFBP data types