KIFAP3

Across TCGA cell cohorts, KIFAP3 mutation is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIFAP3-associated genes across cancer lineages are KRTAP10-5, EQTN, and CAPSL. Each is linked with KIFAP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIFAP3-to-partner and partner-to-KIFAP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, KRTAP10-5 grouped by KIFAP3-low versus KIFAP3-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIFAP3→partner) and Y-score (partner→KIFAP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	KRTAP10-5 →	+0.014	+4.662	<.001	.005	3	2
BLOOD_Myeloma	EQTN →	+0.065	+3.906	<.001	.009	3	1
BLOOD_Myeloma	CAPSL →	+0.061	+3.906	.003	.009	3	1
BLOOD_Myeloma	OPRPN →	+0.042	+4.754	<.001	<.001	3	1
LUNG_SCLC	OR5AU1 →	+0.030	+4.269	<.001	.005	3	1
LUNG_SCLC	FAM25G →	+0.493	+4.269	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

KRTAP10-5 by KIFAP3 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →