KIF9

Across TCGA patient cohorts, KIF9 mutation is significantly associated with the total protein of many other genes, with 41 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF9-associated genes across cancer lineages are Acetyl-a-Tubulin-Lys40, INPP4B, and PDCD4. Each is linked with KIF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF9-to-partner and partner-to-KIF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Acetyl-a-Tubulin-Lys40 grouped by KIF9-low versus KIF9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF9→partner) and Y-score (partner→KIF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.493	+1.938	.003	.001	3	2
UCEC	INPP4B →	-0.232	-1.906	.029	.014	3	2
UCEC	PDCD4 →	-0.510	-2.087	<.001	.004	3	2
UCEC	Caspase-7-cleavedD198 →	+0.728	+3.087	<.001	<.001	3	2
UCEC	c-Met_pY1235 →	+0.073	+1.512	.002	.017	3	2
UCEC	eIF4E →	+0.229	+1.938	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 41 associations by consensus.

Acetyl-a-Tubulin-Lys40 by KIF9 expression — UCEC

Explore this box plot interactively →