KIF9-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, KIF9-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated KIF9-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher KIF9-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated KIF9-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and UCS show a favorable association.

KIRC, UCEC, and MESO are the cancer types where KIF9-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSTertileAll0.5370.701<.001124view →
UCECDFSTertileII,III,IV0.9010.686<.00194view →
MESOOSTertileAll0.2730.537<.00190view →
LUADDFSTertileAll0.7260.849.00151view →
KICHDFSMedianAll0.6970.968.00247view →
ACCDFSQuartileII,III,IV0.4500.795.00337view →
UCSOSMedianIV0.7320.224.01836view →
SKCMDFSTertileII,III,IV0.6690.464.00327view →
LGGDFSQuartileAll0.6940.855<.00124view →
LIHCDFSMedianAll0.2170.339.00820view →
SARCOSTertileAll0.6400.901<.00118view →
BRCADFSTertileIII,IV0.9420.839.01615view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

Exploration