KIF7

Across TCGA cell cohorts, KIF7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,784 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF7-associated GO terms across cancer lineages are Establishment of RNA localization, Nuclear export, and RNA export from nucleus. Each is linked with KIF7 in more than 16 cancer types. Because this analysis shows association rather than direction, both KIF7-to-partner and partner-to-KIF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of RNA localization grouped by KIF7-low versus KIF7-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF7→partner) and Y-score (partner→KIF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Establishment of RNA localization →	+0.118	+1.564	.001	<.001	3	17
UPPER_AERODIGESTIVE_TRACT	Nuclear export →	+0.100	+1.338	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	RNA export from nucleus →	+0.126	+1.369	.001	<.001	3	16
BONE	RNA localization →	+0.117	+1.260	<.001	.007	3	16
BONE	Negative regulation of RNA splicing →	+0.104	+1.584	<.001	<.001	3	15
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.111	+1.404	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,784 associations by consensus.

Establishment of RNA localization by KIF7 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →