KIF7

Across TCGA cell cohorts, KIF7 mutation is significantly associated with the mutation status of many other genes, with 5,673 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF7-associated genes across cancer lineages are CROCC, KCNMA1, and RSF1. Each is linked with KIF7 in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF7-to-partner and partner-to-KIF7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CROCC grouped by KIF7-low versus KIF7-high in OVARY.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF7→partner) and Y-score (partner→KIF7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CROCC →	+3.217	+3.684	.006	.006	1	6
STOMACH	KCNMA1 →	+4.025	+2.942	.009	.009	1	6
SKIN	RSF1 →	+5.053	+4.239	.007	.007	1	5
UPPER_AERODIGESTIVE_TRACT	AGL →	+5.392	+5.392	.004	.004	1	5
OVARY	ITPR3 →	+4.047	+5.099	<.001	<.001	1	5
STOMACH	EIF5B →	+4.025	+2.942	.009	.009	1	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,673 associations by consensus.

CROCC by KIF7 expression — OVARY

Explore this box plot interactively →