KIF6

Across TCGA patient cohorts, KIF6 protein abundance is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF6-associated genes across cancer lineages are DTX4, SPDEF, and DUT. Each is linked with KIF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF6-to-partner and partner-to-KIF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF6 versus DTX4 in LSCC, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF6→partner) and Y-score (partner→KIF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DTX4 →	-1.639	-0.803	.006	.007	3	1
LSCC	SPDEF →	-2.816	-0.803	<.001	.007	3	1
LSCC	DUT →	+1.146	+0.803	<.001	.007	3	1
LSCC	PATJ →	+0.933	+0.636	.005	.006	3	1
LSCC	FANCI →	+1.570	+0.803	.008	.007	3	1
LSCC	ANKRD29 →	+1.920	+0.803	.004	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

KIF6 vs DTX4 — LSCC

Explore this scatter interactively →