KIF6

Across TCGA patient cohorts, KIF6 protein abundance is significantly associated with the protein abundance of many other proteins, with 53 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible KIF6-associated proteins across cancer lineages are GPN1_S338, INPP5D_S971, and ITFG1. Each is linked with KIF6 in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF6-to-partner and partner-to-KIF6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF6 versus GPN1_S338 in LSCC, with a Pearson correlation of 0.65.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF6→partner) and Y-score (partner→KIF6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GPN1_S338 →	+0.899	+0.790	.003	.009	2	1
LSCC	INPP5D_S971 →	-1.276	-0.646	.005	.005	2	1
LSCC	ITFG1 →	-0.800	-0.803	.005	.007	2	1
LSCC	CRTC1_S113 →	-0.986	-0.646	.007	.005	2	1
LSCC	DLG5_S1795 →	+1.706	+0.790	.001	.009	2	1
LSCC	DNTTIP2 →	+0.460	+0.803	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

KIF6 vs GPN1_S338 — LSCC

Explore this scatter interactively →