Across TCGA patient cohorts, KIF4B mutation is significantly associated with the RNA expression of many other genes, with 5,945 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF4B-associated genes across cancer lineages are CDCA2, ZNF695, and UHRF1. Each is linked with KIF4B in more than 3 cancer types. Because this analysis shows association rather than direction, both KIF4B-to-partner and partner-to-KIF4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF4B→partner) and Y-score (partner→KIF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDCA2 →	+0.819	+2.169	<.001	<.001	3	4
COAD	ZNF695 →	+0.392	+2.710	.001	.003	3	4
UCEC	UHRF1 →	+0.990	+2.412	<.001	<.001	3	4
UCEC	WDR76 →	+0.840	+2.684	<.001	<.001	3	4
UCEC	CLSPN →	+0.815	+1.959	<.001	<.001	3	4
UCEC	CDC45 →	+0.807	+2.716	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,945 associations by consensus.

Exploration

KIF4B survival (RNA) · tumor vs normal (RNA) · all KIF4B data types