Across TCGA cell cohorts, KIF4B mutation is significantly associated with the RNA expression of many other genes, with 87 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible KIF4B-associated genes across cancer lineages are TSPAN16, CLEC10A, and GABRA4. Each is linked with KIF4B in more than 1 cancer types. Because this analysis shows association rather than direction, both KIF4B-to-partner and partner-to-KIF4B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF4B→partner) and Y-score (partner→KIF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	TSPAN16 →	+0.042	+4.017	<.001	.007	3	1
OESOPHAGUS	CLEC10A →	+0.019	+4.017	.002	.007	3	1
PANCREAS	GABRA4 →	+0.025	+4.011	.007	.009	3	1
PANCREAS	LALBA →	+0.019	+4.786	<.001	.001	3	1
PANCREAS	ODF4 →	+0.201	+4.786	<.001	.001	3	1
PANCREAS	LRRC10 →	+0.006	+4.011	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 87 associations by consensus.

Exploration

KIF4B survival (RNA) · tumor vs normal (RNA) · all KIF4B data types