KIF3B

Across TCGA pan-cancer cohorts, KIF3B mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated KIF3B data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher KIF3B mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated KIF3B expression acts as an unfavorable survival marker, although some lineages such as COAD and UCEC show a favorable association.

COAD, CCRCC, and UCEC are the cancer types where KIF3B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.911	.015	24	view →
CCRCC	DFS	Quartile	II,III,IV	0.304	0.843	.002	23	view →
UCEC	DFS	Tertile	All	1.000	0.835	.006	12	view →
GBM	DFS	Tertile	All	0.866	0.642	.008	6	view →
LUAD	OS	Tertile	III,IV	0.747	0.209	.044	2	view →
PDAC	OS	Quartile	All	0.937	0.643	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

KIF3B–COAD (DFS)

Open the COAD breakdown →