KIF3B

Across TCGA patient cohorts, KIF3B mutation is significantly associated with the RNA expression of many other genes, with 2,630 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible KIF3B-associated genes across cancer lineages are ORC6, BOLA3, and CACYBP. Each is linked with KIF3B in more than 2 cancer types. Because this analysis shows association rather than direction, both KIF3B-to-partner and partner-to-KIF3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ORC6 grouped by KIF3B-low versus KIF3B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF3B→partner) and Y-score (partner→KIF3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	ORC6 →	+0.646	+3.208	.004	.009	3	3
UCEC	BOLA3 →	+0.329	+3.906	.002	<.001	3	3
UCEC	CACYBP →	+0.547	+1.541	<.001	.002	3	3
UCEC	TIMM17A →	+0.361	+1.942	.008	.002	3	3
BRCA	MTND4P1 →	+0.045	+4.926	<.001	.005	3	2
CESC	NMBR-AS1 →	+0.099	+2.804	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,630 associations by consensus.

ORC6 by KIF3B expression — SKCM

Explore this box plot interactively →