KIF3AP1

Across TCGA pan-cancer cohorts, KIF3AP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of KIF3AP1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where KIF3AP1 RNA is repressed in tumor relative to normal tissue. In most cancer types KIF3AP1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, LUAD, and KICH are the cancer types where KIF3AP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in KIF3AP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	−0.076	<.001	10	view →
LUAD	Female	All	+0.672	<.001	9	view →
KICH	All	All	−0.092	.010	3	view →
PAAD	Female	All	+0.435	.006	2	view →
KIRP	All	All	−0.148	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

KIF3AP1–KIRC

Open the KIRC breakdown →