KIF3A

Across TCGA patient cohorts, KIF3A protein abundance is significantly associated with the RNA expression of many other genes, with 13,144 significant associations in total. GBM shows the largest number of these associations.

The most reproducible KIF3A-associated genes across cancer lineages are KIF3B, IFI30, and SOWAHA. Each is linked with KIF3A in more than 5 cancer types. Because this analysis shows association rather than direction, both KIF3A-to-partner and partner-to-KIF3A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, KIF3A versus KIF3B in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF3A→partner) and Y-score (partner→KIF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF3B →	+0.412	+0.232	<.001	<.001	3	6
UCEC	IFI30 →	-0.631	-0.237	<.001	<.001	3	5
GBM	SOWAHA →	+0.973	+0.288	<.001	<.001	3	5
BRCA	DYNLRB1 →	+0.381	+0.209	<.001	<.001	3	5
BRCA	FITM2 →	+0.828	+0.360	<.001	<.001	3	5
BRCA	HAGH →	+0.570	+0.288	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,144 associations by consensus.

KIF3A vs KIF3B — BRCA

Explore this scatter interactively →