KIF3A

Across TCGA cell cohorts, KIF3A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,346 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible KIF3A-associated GO terms across cancer lineages are Protein localization to cilium, Microtubule anchoring at microtubule organizing center, and Plus-end-directed organelle transport along microtubule. Each is linked with KIF3A in more than 17 cancer types. Because this analysis shows association rather than direction, both KIF3A-to-partner and partner-to-KIF3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by KIF3A-low versus KIF3A-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (KIF3A→partner) and Y-score (partner→KIF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Protein localization to cilium →	+0.084	+1.224	<.001	<.001	3	18
OESOPHAGUS	Microtubule anchoring at microtubule organizing center →	+0.110	+1.167	.004	.003	3	18
BLOOD_Leukemia	Plus-end-directed organelle transport along microtubule →	+0.513	+1.030	<.001	<.001	3	17
BLOOD_Leukemia	Plus-end-directed vesicle transport along microtubule →	+0.415	+1.280	<.001	<.001	3	17
BONE	Microtubule anchoring →	+0.105	+1.061	<.001	<.001	3	17
LARGE_INTESTINE	Microtubule polymerization →	+0.111	+0.743	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,346 associations by consensus.

Protein localization to cilium by KIF3A expression — URINARY_TRACT

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